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Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs
Retroperitoneal paragangliomas are rare tumors of the neuroendocrine system. Only a few canine case reports are available with rare descriptions of their imaging features. The objectives of this multi‐center, retrospective case series study were to describe the diagnostic imaging features of confirm...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546460/ https://www.ncbi.nlm.nih.gov/pubmed/35050528 http://dx.doi.org/10.1111/vru.13063 |
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author | Gombert, Alexis Diana, Alessia Hecht, Silke Nicoli, Stefano Fracassi, Federico Mortier, Jeremy Reyes‐Gomez, Edouard Pey, Pascaline |
author_facet | Gombert, Alexis Diana, Alessia Hecht, Silke Nicoli, Stefano Fracassi, Federico Mortier, Jeremy Reyes‐Gomez, Edouard Pey, Pascaline |
author_sort | Gombert, Alexis |
collection | PubMed |
description | Retroperitoneal paragangliomas are rare tumors of the neuroendocrine system. Only a few canine case reports are available with rare descriptions of their imaging features. The objectives of this multi‐center, retrospective case series study were to describe the diagnostic imaging features of confirmed retroperitoneal paragangliomas and specify their location. Medical records and imaging studies of 10 affected dogs with cytological or histopathologic results concordant with retroperitoneal paragangliomas were evaluated. Dogs had a median age of 9 years. Four of them had clinical signs and laboratory reports compatible with excessive production of catecholamines. Six ultrasound, four CT, four radiographic, and one MRI studies were included. The paragangliomas did not have a specific location along the aorta. They were of various sizes (median 33 mm, range: 9–85 mm of length). Masses had heterogeneous parenchyma in six of 10 dogs, regardless of the imaging modality. Strong contrast enhancement was found in all CT studies. Encircling of at least one vessel was detected in six of 10 masses, clear invasion of a vessel was identified in one of 10 masses. In five of 10 cases, the masses were initially misconstrued as lymph nodes by the on‐site radiologist. Retroperitoneal paragangliomas appear along the abdominal aorta, often presenting heterogeneous parenchyma, possibly affecting the local vasculature, and displaying strong contrast enhancement on CT. Clinical signs can be secondary to mass effects or excessive catecholamine production. Underdiagnosis and misdiagnosis of this tumor are suspected as they can be silent, of small size, or confused with other structures. |
format | Online Article Text |
id | pubmed-9546460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95464602022-10-14 Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs Gombert, Alexis Diana, Alessia Hecht, Silke Nicoli, Stefano Fracassi, Federico Mortier, Jeremy Reyes‐Gomez, Edouard Pey, Pascaline Vet Radiol Ultrasound Diagnostic Radiology, Computed Tomography, Magnetic Resonance Imaging Retroperitoneal paragangliomas are rare tumors of the neuroendocrine system. Only a few canine case reports are available with rare descriptions of their imaging features. The objectives of this multi‐center, retrospective case series study were to describe the diagnostic imaging features of confirmed retroperitoneal paragangliomas and specify their location. Medical records and imaging studies of 10 affected dogs with cytological or histopathologic results concordant with retroperitoneal paragangliomas were evaluated. Dogs had a median age of 9 years. Four of them had clinical signs and laboratory reports compatible with excessive production of catecholamines. Six ultrasound, four CT, four radiographic, and one MRI studies were included. The paragangliomas did not have a specific location along the aorta. They were of various sizes (median 33 mm, range: 9–85 mm of length). Masses had heterogeneous parenchyma in six of 10 dogs, regardless of the imaging modality. Strong contrast enhancement was found in all CT studies. Encircling of at least one vessel was detected in six of 10 masses, clear invasion of a vessel was identified in one of 10 masses. In five of 10 cases, the masses were initially misconstrued as lymph nodes by the on‐site radiologist. Retroperitoneal paragangliomas appear along the abdominal aorta, often presenting heterogeneous parenchyma, possibly affecting the local vasculature, and displaying strong contrast enhancement on CT. Clinical signs can be secondary to mass effects or excessive catecholamine production. Underdiagnosis and misdiagnosis of this tumor are suspected as they can be silent, of small size, or confused with other structures. John Wiley and Sons Inc. 2022-01-20 2022 /pmc/articles/PMC9546460/ /pubmed/35050528 http://dx.doi.org/10.1111/vru.13063 Text en © 2022 The Authors. Veterinary Radiology & Ultrasound published by Wiley Periodicals LLC on behalf of American College of Veterinary Radiology. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Diagnostic Radiology, Computed Tomography, Magnetic Resonance Imaging Gombert, Alexis Diana, Alessia Hecht, Silke Nicoli, Stefano Fracassi, Federico Mortier, Jeremy Reyes‐Gomez, Edouard Pey, Pascaline Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title | Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title_full | Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title_fullStr | Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title_full_unstemmed | Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title_short | Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
title_sort | imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs |
topic | Diagnostic Radiology, Computed Tomography, Magnetic Resonance Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546460/ https://www.ncbi.nlm.nih.gov/pubmed/35050528 http://dx.doi.org/10.1111/vru.13063 |
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