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Human sperm TMEM95 binds eggs and facilitates membrane fusion
Tmem95 encodes a sperm acrosomal membrane protein, whose knockout has a male-specific sterility phenotype in mice. Tmem95 knockout murine sperm can bind to, but do not fuse with, eggs. How TMEM95 plays a role in membrane fusion of sperm and eggs has remained elusive. Here, we utilize a sperm penetra...
Autores principales: | Tang, Shaogeng, Lu, Yonggang, Skinner, Will M., Sanyal, Mrinmoy, Lishko, Polina V., Ikawa, Masahito, Kim, Peter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546558/ https://www.ncbi.nlm.nih.gov/pubmed/36161911 http://dx.doi.org/10.1073/pnas.2207805119 |
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