Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenge currently available coronavirus disease 2019 vaccines and monoclonal antibody therapies through epitope change on the receptor binding domain of the viral spike glycoprotein. Hence, there is a specific urgent need for...

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Detalles Bibliográficos
Autores principales: Yang, Kailu, Wang, Chuchu, Kreutzberger, Alex J. B., Ojha, Ravi, Kuivanen, Suvi, Couoh-Cardel, Sergio, Muratcioglu, Serena, Eisen, Timothy J., White, K. Ian, Held, Richard G., Subramanian, Subu, Marcus, Kendra, Pfuetzner, Richard A., Esquivies, Luis, Doyle, Catherine A., Kuriyan, John, Vapalahti, Olli, Balistreri, Giuseppe, Kirchhausen, Tom, Brunger, Axel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546559/
https://www.ncbi.nlm.nih.gov/pubmed/36122200
http://dx.doi.org/10.1073/pnas.2210990119

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