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Chronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling
Psychological stress has been previously reported to worsen symptoms of inflammatory bowel disease (IBD). Similarly, intestinal tertiary lymphoid organs (TLOs) are associated with more severe inflammation. While there is active debate about the role of TLOs and stress in IBD pathogenesis, there are...
Autores principales: | Gomez-Nguyen, Adrian, Gupta, Nikhilesh, Sanaka, Harsha, Gruszka, Dennis, Pizarro, Alaina, DiMartino, Luca, Basson, Abigail, Menghini, Paola, Osme, Abdullah, DeSalvo, Carlo, Pizarro, Theresa, Cominelli, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546604/ https://www.ncbi.nlm.nih.gov/pubmed/36161939 http://dx.doi.org/10.1073/pnas.2208160119 |
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