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Discovering design principles of collagen molecular stability using a genetic algorithm, deep learning, and experimental validation

Collagen is the most abundant structural protein in humans, providing crucial mechanical properties, including high strength and toughness, in tissues. Collagen-based biomaterials are, therefore, used for tissue repair and regeneration. Utilizing collagen effectively during materials processing ex v...

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Detalles Bibliográficos
Autores principales: Khare, Eesha, Yu, Chi-Hua, Gonzalez Obeso, Constancio, Milazzo, Mario, Kaplan, David L., Buehler, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546622/
https://www.ncbi.nlm.nih.gov/pubmed/36161946
http://dx.doi.org/10.1073/pnas.2209524119