Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca(2+) dynamics in primary skeletal myocytes

Type 1 ryanodine receptor (RYR1) is a Ca(2+) release channel in the sarcoplasmic reticulum (SR) of the skeletal muscle and plays a critical role in excitation–contraction coupling. Mutations in RYR1 cause severe muscle diseases, such as malignant hyperthermia, a disorder of Ca(2+)-induced Ca(2+) rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuboi, Yoshitaka, Oyama, Kotaro, Kobirumaki-Shimozawa, Fuyu, Murayama, Takashi, Kurebayashi, Nagomi, Tachibana, Toshiaki, Manome, Yoshinobu, Kikuchi, Emi, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Mori, Shuichi, Ishida, Ryosuke, Kagechika, Hiroyuki, Suzuki, Madoka, Fukuda, Norio, Yamazawa, Toshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546722/
https://www.ncbi.nlm.nih.gov/pubmed/36200983
http://dx.doi.org/10.1085/jgp.202213136

Ejemplares similares

Ejemplares similares