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The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made significant impacts on global public health, including the development of several skin diseases that have arisen primarily as a result of the pandemic. Owing to the widespread expansion of coronavirus disease 19 (COVID-19), the de...

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Autores principales: Yang, Seoyoun, Han, Su Bin, Kang, Soohyun, Lee, Junghyun, Kim, Dongseon, Kozlova, Anastasiia, Song, Minkyung, Park, See-Hyoung, Lee, Jongsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546782/
https://www.ncbi.nlm.nih.gov/pubmed/36249949
http://dx.doi.org/10.1016/j.jgr.2022.09.010
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author Yang, Seoyoun
Han, Su Bin
Kang, Soohyun
Lee, Junghyun
Kim, Dongseon
Kozlova, Anastasiia
Song, Minkyung
Park, See-Hyoung
Lee, Jongsung
author_facet Yang, Seoyoun
Han, Su Bin
Kang, Soohyun
Lee, Junghyun
Kim, Dongseon
Kozlova, Anastasiia
Song, Minkyung
Park, See-Hyoung
Lee, Jongsung
author_sort Yang, Seoyoun
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made significant impacts on global public health, including the development of several skin diseases that have arisen primarily as a result of the pandemic. Owing to the widespread expansion of coronavirus disease 19 (COVID-19), the development of effective treatments for these skin diseases is drawing attention as an important social issue. For many centuries, ginseng and its major active ingredients, ginsenosides and saponins, have been widely regarded as herbal medicines. Further, the anti-viral action of ginseng suggests its potential effectiveness as a therapeutic agent against COVID-19. Thus, the aim of this review was to examine the association of skin lesions with COVID-19 and the effect of ginseng as a therapeutic agent to treat skin diseases induced by COVID-19 infection. We classified COVID-19-related skin disorders into three categories: caused by inflammatory, immune, and complex (both inflammatory and immune) responses and evaluated the evidence for ginseng as a treatment for each category. This review offers comprehensive evidence on the improvement of skin disorders induced by SARS-CoV-2 infection using ginseng and its active constituents.
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spelling pubmed-95467822022-10-11 The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review Yang, Seoyoun Han, Su Bin Kang, Soohyun Lee, Junghyun Kim, Dongseon Kozlova, Anastasiia Song, Minkyung Park, See-Hyoung Lee, Jongsung J Ginseng Res Review Article Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made significant impacts on global public health, including the development of several skin diseases that have arisen primarily as a result of the pandemic. Owing to the widespread expansion of coronavirus disease 19 (COVID-19), the development of effective treatments for these skin diseases is drawing attention as an important social issue. For many centuries, ginseng and its major active ingredients, ginsenosides and saponins, have been widely regarded as herbal medicines. Further, the anti-viral action of ginseng suggests its potential effectiveness as a therapeutic agent against COVID-19. Thus, the aim of this review was to examine the association of skin lesions with COVID-19 and the effect of ginseng as a therapeutic agent to treat skin diseases induced by COVID-19 infection. We classified COVID-19-related skin disorders into three categories: caused by inflammatory, immune, and complex (both inflammatory and immune) responses and evaluated the evidence for ginseng as a treatment for each category. This review offers comprehensive evidence on the improvement of skin disorders induced by SARS-CoV-2 infection using ginseng and its active constituents. Elsevier 2023-01 2022-10-08 /pmc/articles/PMC9546782/ /pubmed/36249949 http://dx.doi.org/10.1016/j.jgr.2022.09.010 Text en © 2022 The Korean Society of Ginseng. Publishing services by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Yang, Seoyoun
Han, Su Bin
Kang, Soohyun
Lee, Junghyun
Kim, Dongseon
Kozlova, Anastasiia
Song, Minkyung
Park, See-Hyoung
Lee, Jongsung
The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title_full The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title_fullStr The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title_full_unstemmed The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title_short The relationship of skin disorders, COVID-19, and the therapeutic potential of ginseng: a review
title_sort relationship of skin disorders, covid-19, and the therapeutic potential of ginseng: a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546782/
https://www.ncbi.nlm.nih.gov/pubmed/36249949
http://dx.doi.org/10.1016/j.jgr.2022.09.010
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