Cargando…

Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation

Controlled in vitro multicellular culture systems with defined biophysical microenvironment have been used to elucidate the role of Notch signaling in the spatiotemporal regulation of stem and progenitor cell differentiation. In addition, computational models incorporating features of Notch ligand-r...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Ishita, Berg, Ian C., Acharya, Ayusha, Blaauw, Maddie, Gosstola, Nicholas, Perez-Pinera, Pablo, Underhill, Gregory H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546876/
https://www.ncbi.nlm.nih.gov/pubmed/36207581
http://dx.doi.org/10.1038/s42003-022-03840-9