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Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation
Controlled in vitro multicellular culture systems with defined biophysical microenvironment have been used to elucidate the role of Notch signaling in the spatiotemporal regulation of stem and progenitor cell differentiation. In addition, computational models incorporating features of Notch ligand-r...
Autores principales: | Jain, Ishita, Berg, Ian C., Acharya, Ayusha, Blaauw, Maddie, Gosstola, Nicholas, Perez-Pinera, Pablo, Underhill, Gregory H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546876/ https://www.ncbi.nlm.nih.gov/pubmed/36207581 http://dx.doi.org/10.1038/s42003-022-03840-9 |
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