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Circulating tumor DNA in Hodgkin lymphoma

Somatic mutations of genes involved in NF-κB, PI3K/AKT, NOTCH, and JAK/STAT signaling pathways play an important role in the pathogenesis of Hodgkin lymphoma (HL). HL tumor cells form only about 5% of the tumor mass; however, it was shown that HL tumor-derived DNA could be detected in the bloodstrea...

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Detalles Bibliográficos
Autores principales: Maco, Maria, Kupcova, Kristyna, Herman, Vaclav, Ondeckova, Iva, Kozak, Tomas, Mocikova, Heidi, Havranek, Ondrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9546971/
https://www.ncbi.nlm.nih.gov/pubmed/36074181
http://dx.doi.org/10.1007/s00277-022-04949-x