C/D box snoRNA SNORD113-6 guides 2′-O-methylation and protects against site-specific fragmentation of tRNA(Leu)(TAA) in vascular remodeling

C/D box small nucleolar RNAs (snoRNAs) of the DLK1-DIO3 locus are associated with vascular remodeling and cardiovascular disease. None of these snoRNAs has any known targets yet except for one, AF357425/SNORD113-6. We previously showed that this snoRNA targets mRNAs of the integrin signaling pathway...

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Detalles Bibliográficos
Autores principales: van Ingen, Eva, Engbers, Pleun A.M., Woudenberg, Tamar, van der Bent, M. Leontien, Mei, Hailiang, Wojta, Johann, Quax, Paul H.A., Nossent, A. Yaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547152/
https://www.ncbi.nlm.nih.gov/pubmed/36250206
http://dx.doi.org/10.1016/j.omtn.2022.09.011

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