Cargando…

Ki-67, topoisomerase IIα and miR-221 have a limited prostate cancer risk stratification ability on a medium-term follow-up: results of a high-risk radical prostatectomy cohort

BACKGROUND: Currently, no biomarkers are able to differentiate lethal from relatively indolent prostate cancer (PCa) within high-risk diseases. Nonetheless, several molecules are under investigation. Amongst them, topoisomerase-II-alpha (TOPIIA), Ki67 and miR-221 showed promising results. Our aim wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marra, Giancarlo, Oderda, Marco, Calleris, Giorgio, Marquis, Alessandro, Peretti, Federica, Zitella, Andrea, Moschini, Marco, Sanchez-Salas, Rafael, Karnes, Robert Jeffrey, Kneitz, Burkhard, Spahn, Martin, Pacchioni, Donatella, Gontero, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547160/ https://www.ncbi.nlm.nih.gov/pubmed/36217395 http://dx.doi.org/10.21037/tau-21-628

Ejemplares similares

Intraoperative 3D-US-mpMRI Elastic Fusion Imaging-Guided Robotic Radical Prostatectomy: A Pilot Study
por: Oderda, Marco, et al.
Publicado: (2022)

Safety and Feasibility of Transperineal Targeted Microwave Ablation for Low- to Intermediate-risk Prostate Cancer
por: Oderda, Marco, et al.
Publicado: (2022)

Nightmares in Salvage Robot-assisted Radical Prostatectomy After Primary Radiation Therapy for Prostate Cancer: A Step by Step Tutorial
por: Marquis, Alessandro, et al.
Publicado: (2022)

Predictors of Prostate Cancer at Fusion Biopsy: The Role of Positive Family History, Hypertension, Diabetes, and Body Mass Index
por: Oderda, Marco, et al.
Publicado: (2023)

Topography of Prostate Cancer Recurrence: A Single-centre Analysis of Salvage Radical Prostatectomy Specimens and Implications for Focal Salvage Treatments
por: Marra, Giancarlo, et al.
Publicado: (2022)

Awake Da Vinci robotic partial nephrectomy: First case report ever in a situation of need
por: Gontero, Paolo, et al.
Publicado: (2022)

Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort
por: Richardsen, Elin, et al.
Publicado: (2017)

How uro-oncology has been affected by COVID-19 emergency? Data from Piedmont/Valle d’Aosta Oncological Network, Italy
por: Oderda, Marco, et al.
Publicado: (2021)

DNA topoisomerase IIα and Ki67 are prognostic factors in patients with hepatocellular carcinoma
por: Cao, Yi, et al.
Publicado: (2017)

COVID-19 pandemic impact on uro-oncological disease outcomes at an Italian tertiary referral center
por: Oderda, Marco, et al.
Publicado: (2021)

Machine Learning-Based Prediction of Pathological Upgrade From Combined Transperineal Systematic and MRI-Targeted Prostate Biopsy to Final Pathology: A Multicenter Retrospective Study
por: Zhuang, Junlong, et al.
Publicado: (2022)

Impact of operator expertise on transperineal free-hand mpMRI-fusion-targeted biopsies under local anaesthesia for prostate cancer diagnosis: a multicenter prospective learning curve
por: Calleris, Giorgio, et al.
Publicado: (2023)

Adrenal Ganglioneuroma with Multifocal Retroperitoneal Extension: A Challenging Diagnosis
por: Oderda, Marco, et al.
Publicado: (2011)

Low Levels of Urinary PSA Better Identify Prostate Cancer Patients
por: Occhipinti, Sergio, et al.
Publicado: (2021)

Incorporation of tissue-based genomic biomarkers into localized prostate cancer clinics
por: Moschini, Marco, et al.
Publicado: (2016)

miR-221-3p Regulates VEGFR2 Expression in High-Risk Prostate Cancer and Represents an Escape Mechanism from Sunitinib In Vitro
por: Krebs, Markus, et al.
Publicado: (2020)

Can p53, Ki-67 and bcl-2 predict biochemical failure after radical prostatectomy?
por: Baseskioglu, B., et al.
Publicado: (2010)

Comparison of digital image analysis and visual scoring of KI-67 in prostate cancer prognosis after prostatectomy
por: Desmeules, Patrice, et al.
Publicado: (2015)

Ki-67 expression predicts biochemical recurrence after radical prostatectomy in the setting of positive surgical margins
por: Shahait, Mohammed, et al.
Publicado: (2018)

Ki-67 gene expression
por: Uxa, Sigrid, et al.
Publicado: (2021)

The SAFE Pilot Trial—SAlvage Focal Irreversible Electroporation—For Recurrent Localized Prostate Cancer: Rationale and Study Protocol
por: Marra, Giancarlo, et al.
Publicado: (2022)

To Ki or Not to Ki: Re-Evaluating the Use and Potentials of Ki-67 for T Cell Analysis
por: Di Rosa, Francesca, et al.
Publicado: (2021)

DKK-1 in prostate cancer diagnosis and follow up
por: D’Amelio, Patrizia, et al.
Publicado: (2014)

The Impact of COVID-19 Outbreak on Uro-oncological Practice Across Europe: Which Burden of Activity Are We Facing Ahead?
por: Oderda, Marco, et al.
Publicado: (2020)

What is the Need for Prostatic Biomarkers in Prostate Cancer Management?
por: Spahn, Martin, et al.
Publicado: (2015)

P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas
por: Sundov, Dinka, et al.
Publicado: (2013)

Corrigendum: To Ki or Not to Ki: Re-Evaluating the Use and Potentials of Ki-67 for T Cell Analysis
por: Di Rosa, Francesca, et al.
Publicado: (2021)

The intrinsically disorderly story of Ki-67
por: Remnant, Lucy, et al.
Publicado: (2021)

Oncologic Outcomes of Lymph Node Dissection at Salvage Radical Prostatectomy
por: Preisser, Felix, et al.
Publicado: (2023)

Proliferative activity in human breast cancer: Ki-67 automated evaluation and the influence of different Ki-67 equivalent antibodies
por: Fasanella, S, et al.
Publicado: (2011)

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group
por: Nielsen, Torsten O, et al.
Publicado: (2020)

The Potential Value of Ki-67 in Prognostic Classification in Early Low-Risk Endometrial Cancer
por: Jia, Mingzhu, et al.
Publicado: (2023)

67. INCREASED RISK OF BREAST CANCER BRAIN METASTASIS WITH EGFR AND Ki-67 EXPRESSION: A SYSTEMATIC REVIEW AND META-ANALYSIS
por: Job, Arun, et al.
Publicado: (2020)

Immunolocalization of Ki-67 in different periodontal conditions
por: Preethi, Penubolu Lakshmi, et al.
Publicado: (2014)

Impact of Lymph Node Burden on Survival of High-risk Prostate Cancer Patients Following Radical Prostatectomy and Pelvic Lymph Node Dissection
por: Moris, Lisa, et al.
Publicado: (2016)

Quantum Dots-Based Quantitative and In Situ Multiple Imaging on Ki67 and Cytokeratin to Improve Ki67 Assessment in Breast Cancer
por: Yuan, Jing Ping, et al.
Publicado: (2015)

ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling
por: Barricelli, Barbara Rita, et al.
Publicado: (2019)

Independent Clinical Validation of the Automated Ki67 Scoring Guideline from the International Ki67 in Breast Cancer Working Group
por: Boyaci, Ceren, et al.
Publicado: (2021)

Low correlation between Ki67 assessed by qRT-PCR in Oncotype Dx score and Ki67 assessed by Immunohistochemistry
por: Selmani, Zohair, et al.
Publicado: (2022)

Ki-67 and breast cancer prognosis: does it matter if Ki-67 level is examined using preoperative biopsy or postoperative specimen?
por: Choi, Soon Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1ev5or9pma8kkhesu47ne75qac