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Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals

Peimine, a bioactive substance isolated from Chinese medicine Fritillaria, can potentially suppress pulmonary fibrosis (PF); however, its therapeutic mechanism remains unclear. Recent evidence suggests the participation of M2-type macrophages in the pathogenesis of PF. The present study aimed to inv...

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Detalles Bibliográficos
Autores principales: Cai, Ze-hui, Tian, Yan-ge, Li, Jun-zi, Zhao, Peng, Li, Jian-sheng, Mei, Xue, Bai, Yun-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547170/
https://www.ncbi.nlm.nih.gov/pubmed/36111628
http://dx.doi.org/10.1042/BSR20220986