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Peimine ameliorates pulmonary fibrosis via the inhibition of M2-type macrophage polarization through the suppression of P38/Akt/STAT6 signals
Peimine, a bioactive substance isolated from Chinese medicine Fritillaria, can potentially suppress pulmonary fibrosis (PF); however, its therapeutic mechanism remains unclear. Recent evidence suggests the participation of M2-type macrophages in the pathogenesis of PF. The present study aimed to inv...
Autores principales: | Cai, Ze-hui, Tian, Yan-ge, Li, Jun-zi, Zhao, Peng, Li, Jian-sheng, Mei, Xue, Bai, Yun-ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547170/ https://www.ncbi.nlm.nih.gov/pubmed/36111628 http://dx.doi.org/10.1042/BSR20220986 |
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