Covalent conjugation of ubiquitin-like ISG15 to apoptosis-inducing factor exacerbates toxic stimuli-induced apoptotic cell death

Apoptosis-inducing factor (AIF) is a mitochondrion-localized flavoprotein with NADH oxidase activity. AIF normally acts as an oxidoreductase to catalyze the transfer of electrons between molecules, but it can also kill cells when exposed to certain stimuli. For example, intact AIF is cleaved upon ex...

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Detalles Bibliográficos
Autores principales: Jeon, Seo Jeong, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547223/
https://www.ncbi.nlm.nih.gov/pubmed/36075291
http://dx.doi.org/10.1016/j.jbc.2022.102464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547223/
https://www.ncbi.nlm.nih.gov/pubmed/36075291
http://dx.doi.org/10.1016/j.jbc.2022.102464

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