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Leveraging omics data to boost the power of genome-wide association studies
Genome-wide association studies (GWASs) have successfully identified many genetic variants and risk loci for complex traits and common diseases in the last 15 years. However, these identified variants, in general, can explain only a small to moderate proportion of the heritability, thus the task of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547296/ https://www.ncbi.nlm.nih.gov/pubmed/36217425 http://dx.doi.org/10.1016/j.xhgg.2022.100144 |