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Leveraging omics data to boost the power of genome-wide association studies

Genome-wide association studies (GWASs) have successfully identified many genetic variants and risk loci for complex traits and common diseases in the last 15 years. However, these identified variants, in general, can explain only a small to moderate proportion of the heritability, thus the task of...

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Detalles Bibliográficos
Autores principales: Lin, Zhaotong, Knutson, Katherine A., Pan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547296/
https://www.ncbi.nlm.nih.gov/pubmed/36217425
http://dx.doi.org/10.1016/j.xhgg.2022.100144