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In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials
RNA–protein interactions are crucial for diverse biological processes. In prokaryotes, RNA–protein interactions enable adaptive immunity through CRISPR-Cas systems. These defence systems utilize CRISPR RNA (crRNA) templates acquired from past infections to destroy foreign genetic elements through cr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547417/ https://www.ncbi.nlm.nih.gov/pubmed/36207756 http://dx.doi.org/10.1186/s13062-022-00339-5 |