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In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials

RNA–protein interactions are crucial for diverse biological processes. In prokaryotes, RNA–protein interactions enable adaptive immunity through CRISPR-Cas systems. These defence systems utilize CRISPR RNA (crRNA) templates acquired from past infections to destroy foreign genetic elements through cr...

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Detalles Bibliográficos
Autores principales: Park, Ho-min, Park, Yunseol, Berani, Urta, Bang, Eunkyu, Vankerschaver, Joris, Van Messem, Arnout, De Neve, Wesley, Shim, Hyunjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547417/
https://www.ncbi.nlm.nih.gov/pubmed/36207756
http://dx.doi.org/10.1186/s13062-022-00339-5