Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis

Neurofibromatosis type 1 is characterized by multiple cutaneous neurofibromas of varying sizes along with skeletal, neurologic, and ophthalmic features. Solitary swellings in neurofibromatosis type 1 are not commonly encountered except in the form of plexiform neurofibromas. We report two cases with...

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Autores principales: Thomas, Irene N, Balasundaram, Amutha, James, Joseph Jenson, Shanmugam, Nithya Priyadharshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547610/
https://www.ncbi.nlm.nih.gov/pubmed/36237736
http://dx.doi.org/10.7759/cureus.28938
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author Thomas, Irene N
Balasundaram, Amutha
James, Joseph Jenson
Shanmugam, Nithya Priyadharshini
author_facet Thomas, Irene N
Balasundaram, Amutha
James, Joseph Jenson
Shanmugam, Nithya Priyadharshini
author_sort Thomas, Irene N
collection PubMed
description Neurofibromatosis type 1 is characterized by multiple cutaneous neurofibromas of varying sizes along with skeletal, neurologic, and ophthalmic features. Solitary swellings in neurofibromatosis type 1 are not commonly encountered except in the form of plexiform neurofibromas. We report two cases with neurofibromatosis type 1 presenting with solitary swelling in the ankles which were proven to be the diffuse type of neurofibroma, radiologically and histopathologically. Diffuse type neurofibroma presenting as ankle swelling in type 1 neurofibromatosis has not been reported before.
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spelling pubmed-95476102022-10-12 Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis Thomas, Irene N Balasundaram, Amutha James, Joseph Jenson Shanmugam, Nithya Priyadharshini Cureus Dermatology Neurofibromatosis type 1 is characterized by multiple cutaneous neurofibromas of varying sizes along with skeletal, neurologic, and ophthalmic features. Solitary swellings in neurofibromatosis type 1 are not commonly encountered except in the form of plexiform neurofibromas. We report two cases with neurofibromatosis type 1 presenting with solitary swelling in the ankles which were proven to be the diffuse type of neurofibroma, radiologically and histopathologically. Diffuse type neurofibroma presenting as ankle swelling in type 1 neurofibromatosis has not been reported before. Cureus 2022-09-08 /pmc/articles/PMC9547610/ /pubmed/36237736 http://dx.doi.org/10.7759/cureus.28938 Text en Copyright © 2022, Thomas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Thomas, Irene N
Balasundaram, Amutha
James, Joseph Jenson
Shanmugam, Nithya Priyadharshini
Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title_full Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title_fullStr Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title_full_unstemmed Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title_short Ankle Swelling in Patients With Type 1 Neurofibromatosis: A Report of Two Cases With Rare Presentation of Common Genodermatosis
title_sort ankle swelling in patients with type 1 neurofibromatosis: a report of two cases with rare presentation of common genodermatosis
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547610/
https://www.ncbi.nlm.nih.gov/pubmed/36237736
http://dx.doi.org/10.7759/cureus.28938
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AT jamesjosephjenson ankleswellinginpatientswithtype1neurofibromatosisareportoftwocaseswithrarepresentationofcommongenodermatosis
AT shanmugamnithyapriyadharshini ankleswellinginpatientswithtype1neurofibromatosisareportoftwocaseswithrarepresentationofcommongenodermatosis

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