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The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients

Background: Core needle biopsy (CNB) guided by imaging modalities seems to be an acceptable modality for diagnosis of lymphoma due to its safety, good applicability, availability as well as diagnostic accuracy, however; Studies have not reached a consensus on its diagnostic accuracy and factors affe...

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Autores principales: Kazemi, Mohammad Ali, Yazdani, Farzad, Sharifian, Hashem, Aghazadeh, Keyvan, Moradi, Behnaz, Behravan, Hengameh, Mikelani, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547778/
https://www.ncbi.nlm.nih.gov/pubmed/36304734
http://dx.doi.org/10.18502/ijhoscr.v16i2.9200
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author Kazemi, Mohammad Ali
Yazdani, Farzad
Sharifian, Hashem
Aghazadeh, Keyvan
Moradi, Behnaz
Behravan, Hengameh
Mikelani, Mohsen
author_facet Kazemi, Mohammad Ali
Yazdani, Farzad
Sharifian, Hashem
Aghazadeh, Keyvan
Moradi, Behnaz
Behravan, Hengameh
Mikelani, Mohsen
author_sort Kazemi, Mohammad Ali
collection PubMed
description Background: Core needle biopsy (CNB) guided by imaging modalities seems to be an acceptable modality for diagnosis of lymphoma due to its safety, good applicability, availability as well as diagnostic accuracy, however; Studies have not reached a consensus on its diagnostic accuracy and factors affecting its performance. The present study aimed to assess the value of ultrasound-guided cervical CNB in the diagnosis of lymphoma in suspected patients. Materials and Methods: This cross-sectional study was performed on 46 consecutive patients (20 to 82 years) with cervical mass or lymphadenopathy suspected of lymphoma and were candidates for diagnostic evaluation. Ultrasound-guided core needle biopsies (UGCNB) were done by a single radiologist under guided ultrasonography. The diagnostic value of UGCNB in the diagnosis and determination of specific lymphoma subtypes was assessed. Results: Using UGCNB led to the diagnosis of lymphoma in 34.8% and non-lymphoma lesions in 43.5%, while the diagnosis remained unclear in other 21.7% with a total UGCNB-based identification rate of 78.3%. No patient with lymphoma was missed. All patients were followed up over a 6-month period. In none of the cases, clinical diagnosis and treatment response were found contrary to the initial pathologic diagnosis. No significant complication such as hematoma or infection was reported. Conclusion: UGCNB has a high diagnostic value for determining the nature of the cervical lesions suspected of lymphoma. 
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spelling pubmed-95477782022-10-26 The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients Kazemi, Mohammad Ali Yazdani, Farzad Sharifian, Hashem Aghazadeh, Keyvan Moradi, Behnaz Behravan, Hengameh Mikelani, Mohsen Int J Hematol Oncol Stem Cell Res Original Article Background: Core needle biopsy (CNB) guided by imaging modalities seems to be an acceptable modality for diagnosis of lymphoma due to its safety, good applicability, availability as well as diagnostic accuracy, however; Studies have not reached a consensus on its diagnostic accuracy and factors affecting its performance. The present study aimed to assess the value of ultrasound-guided cervical CNB in the diagnosis of lymphoma in suspected patients. Materials and Methods: This cross-sectional study was performed on 46 consecutive patients (20 to 82 years) with cervical mass or lymphadenopathy suspected of lymphoma and were candidates for diagnostic evaluation. Ultrasound-guided core needle biopsies (UGCNB) were done by a single radiologist under guided ultrasonography. The diagnostic value of UGCNB in the diagnosis and determination of specific lymphoma subtypes was assessed. Results: Using UGCNB led to the diagnosis of lymphoma in 34.8% and non-lymphoma lesions in 43.5%, while the diagnosis remained unclear in other 21.7% with a total UGCNB-based identification rate of 78.3%. No patient with lymphoma was missed. All patients were followed up over a 6-month period. In none of the cases, clinical diagnosis and treatment response were found contrary to the initial pathologic diagnosis. No significant complication such as hematoma or infection was reported. Conclusion: UGCNB has a high diagnostic value for determining the nature of the cervical lesions suspected of lymphoma.  Tehran University of Medical Sciences, Hematology-Oncology and Stem Cell Transplantation Research Center 2022-04-01 /pmc/articles/PMC9547778/ /pubmed/36304734 http://dx.doi.org/10.18502/ijhoscr.v16i2.9200 Text en Copyright © 2022 Tehran University of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Kazemi, Mohammad Ali
Yazdani, Farzad
Sharifian, Hashem
Aghazadeh, Keyvan
Moradi, Behnaz
Behravan, Hengameh
Mikelani, Mohsen
The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title_full The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title_fullStr The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title_full_unstemmed The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title_short The Diagnostic Value of Ultrasound-Guided Cervical Core Needle Biopsy in Diagnosis of Lymphoma in Suspected Patients
title_sort diagnostic value of ultrasound-guided cervical core needle biopsy in diagnosis of lymphoma in suspected patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547778/
https://www.ncbi.nlm.nih.gov/pubmed/36304734
http://dx.doi.org/10.18502/ijhoscr.v16i2.9200
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