Cargando…
DIALOGUE maps multicellular programs in tissue from single-cell or spatial transcriptomics data
Deciphering the functional interactions of cells in tissues remains a major challenge. We describe DIALOGUE, a method to systematically uncover multicellular programs (MCPs) — combinations of coordinated cellular programs in different cell types that form higher-order functional units at the tissue...
Autores principales: | Jerby-Arnon, Livnat, Regev, Aviv |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547813/ https://www.ncbi.nlm.nih.gov/pubmed/35513526 http://dx.doi.org/10.1038/s41587-022-01288-0 |
Ejemplares similares
-
Moving ahead on harnessing synthetic lethality to fight cancer
por: Jerby-Arnon, Livnat, et al.
Publicado: (2015) -
Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
por: Jerby, Livnat, et al.
Publicado: (2010) -
Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program
por: Muñoz-Dorado, José, et al.
Publicado: (2019) -
Combinatorial prediction of marker panels from single‐cell transcriptomic data
por: Delaney, Conor, et al.
Publicado: (2019) -
Validation of Immune Cell Modules in Multicellular Transcriptomic Data
por: Pollara, Gabriele, et al.
Publicado: (2017)