Cargando…

Signaling pathways and therapeutic interventions in gastric cancer

Gastric cancer (GC) ranks fifth in global cancer diagnosis and fourth in cancer-related death. Despite tremendous progress in diagnosis and therapeutic strategies and significant improvements in patient survival, the low malignancy stage is relatively asymptomatic and many GC cases are diagnosed at...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Zi-Ning, Teng, Qiu-Xu, Tian, Qin, Chen, Wei, Xie, Yuhao, Wu, Kaiming, Zeng, Qianlin, Zeng, Leli, Pan, Yihang, Chen, Zhe-Sheng, He, Yulong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547882/ https://www.ncbi.nlm.nih.gov/pubmed/36209270 http://dx.doi.org/10.1038/s41392-022-01190-w

Ejemplares similares

Understanding and targeting resistance mechanisms in cancer
por: Lei, Zi‐Ning, et al.
Publicado: (2023)

Venetoclax, a BCL-2 Inhibitor, Enhances the Efficacy of Chemotherapeutic Agents in Wild-Type ABCG2-Overexpression-Mediated MDR Cancer Cells
por: Wang, Jing-Quan, et al.
Publicado: (2020)

Overexpression of ABCG2 Confers Resistance to MLN7243, a Ubiquitin-Activating Enzyme (UAE) Inhibitor
por: Wu, Zhuo-Xun, et al.
Publicado: (2021)

Engineering Bifunctional Calcium Alendronate Gene‐Delivery Nanoneedle for Synergistic Chemo/Immuno‐Therapy Against HER2 Positive Ovarian Cancer
por: Chen, Guochuang, et al.
Publicado: (2023)

Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells
por: Zhang, Wei, et al.
Publicado: (2018)

Epitranscriptomics and epiproteomics in cancer drug resistance: therapeutic implications
por: Song, Huibin, et al.
Publicado: (2020)

Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter
por: Gao, Hai-Ling, et al.
Publicado: (2020)

APY0201 Represses Tumor Growth through Inhibiting Autophagy in Gastric Cancer Cells
por: Li, Huan, et al.
Publicado: (2022)

Modulating the function of ABCB1: in vitro and in vivo characterization of sitravatinib, a tyrosine kinase inhibitor
por: Yang, Yuqi, et al.
Publicado: (2020)

Association of metabolic syndrome and the risk of bladder cancer: A prospective cohort study
por: Fang, Shuo, et al.
Publicado: (2022)

Establishment and Characterization of an Irinotecan-Resistant Human Colon Cancer Cell Line
por: Wu, Zhuo-Xun, et al.
Publicado: (2021)

PUM1 Promotes Tumor Progression by Activating DEPTOR‐Meditated Glycolysis in Gastric Cancer
por: Yin, Songcheng, et al.
Publicado: (2023)

Comprehensive analysis to construct a novel immune-related prognostic panel in aging-related gastric cancer based on the lncRNA‒miRNA-mRNA ceRNA network
por: Deng, Cuncan, et al.
Publicado: (2023)

Oncosis-inducing cyclometalated iridium(iii) complexes
por: Guan, Ruilin, et al.
Publicado: (2018)

Survival of Proper Hepatic Artery Lymph Node Metastasis in Patients with Gastric Cancer: Implications for D2 Lymphadenectomy
por: Shirong, Cai, et al.
Publicado: (2015)

Long non-coding RNAs regulate drug resistance in cancer
por: Liu, Kaisheng, et al.
Publicado: (2020)

Combining Organoid Models with Next-Generation Sequencing to Reveal Tumor Heterogeneity and Predict Therapeutic Response in Breast Cancer
por: Liu, Yuhong, et al.
Publicado: (2022)

Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors
por: Wang, Si‐Qi, et al.
Publicado: (2023)

Insights on the structure–function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies
por: Wang, Jing‐Quan, et al.
Publicado: (2021)

Advancements in nanoparticle-based treatment approaches for skin cancer therapy
por: Zeng, Leli, et al.
Publicado: (2023)

Immune Infiltration, Cancer Stemness, and Targeted Therapy in Gastrointestinal Stromal Tumor
por: Wang, Jingjing, et al.
Publicado: (2021)

In vivo synergistic tumor therapies based on copper sulfide photothermal therapeutic nanoplatforms
por: Ma, Jingwen, et al.
Publicado: (2023)

Changes of blood glucose and gastrointestinal hormones 4 months after Roux‐en‐Y gastric bypass surgery in Chinese obese type 2 diabetes patients with lower body mass index
por: Wu, Qianlin, et al.
Publicado: (2012)

Comprehensive analysis of 33 human cancers reveals clinical implications and immunotherapeutic value of the solute carrier family 35 member A2
por: Xu, Shengshan, et al.
Publicado: (2023)

Overcoming multidrug resistance by knockout of ABCB1 gene using CRISPR/Cas9 system in SW620/Ad300 colorectal cancer cells
por: Lei, Zi‐Ning, et al.
Publicado: (2021)

The Resistance of Cancer Cells to Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, is Mediated by the ABCB1 Transporter
por: Fu, Han, et al.
Publicado: (2022)

Effectiveness, nephrotoxicity, and therapeutic drug monitoring of polymyxin B in nosocomial pneumonia among critically ill patients
por: Ye, Qinghua, et al.
Publicado: (2022)

Osimertinib (AZD9291), a Mutant-Selective EGFR Inhibitor, Reverses ABCB1-Mediated Drug Resistance in Cancer Cells
por: Zhang, Xiao-Yu, et al.
Publicado: (2016)

The biological functions and metabolic pathways of valine in swine
por: Wang, Chuni, et al.
Publicado: (2023)

PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study
por: Yang, Yuqi, et al.
Publicado: (2022)

Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance
por: Luo, Xiaofang, et al.
Publicado: (2020)

The cancer-associated fibroblast-related signature predicts prognosis and indicates immune microenvironment infiltration in gastric cancer
por: Mak, Tsz Kin, et al.
Publicado: (2022)

Mechanism of N-Methyl-N-Nitroso-Urea-Induced Gastric Precancerous Lesions in Mice
por: Zhang, Sheng-Xiong, et al.
Publicado: (2022)

Frizzled Receptors as Potential Therapeutic Targets in Human Cancers
por: Zeng, Chui-Mian, et al.
Publicado: (2018)

Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
por: Jiang, Xiuli, et al.
Publicado: (2018)

Mechanisms Underlying Therapeutic Effects Of Traditional Chinese Medicine On Gastric Cancer
por: Yang, Linjun, et al.
Publicado: (2019)

Targeting Ferroptosis as a Promising Therapeutic Strategy for Ischemia-Reperfusion Injury
por: Pan, Yihang, et al.
Publicado: (2022)

Lipid–Saporin Nanoparticles for the Intracellular Delivery of Cytotoxic Protein to Overcome ABC Transporter-Mediated Multidrug Resistance In Vitro and In Vivo
por: Zhang, Guan-Nan, et al.
Publicado: (2020)

The origin of gastric cancer stem cells and their effects on gastric cancer: Novel therapeutic targets for gastric cancer
por: Yang, Ying, et al.
Publicado: (2022)

VS-4718 Antagonizes Multidrug Resistance in ABCB1- and ABCG2-Overexpressing Cancer Cells by Inhibiting the Efflux Function of ABC Transporters
por: Ji, Ning, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rjbnmo2b7oe1jhlgsummsq1rds