Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease

Dysregulation of sphingomyelin and ceramide metabolism have been implicated in Alzheimer’s disease. Genome-wide and transcriptome-wide association studies have identified various genes and genetic variants in lipid metabolism that are associated with Alzheimer’s disease. However, the molecular mecha...

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Detalles Bibliográficos
Autores principales: Baloni, Priyanka, Arnold, Matthias, Buitrago, Luna, Nho, Kwangsik, Moreno, Herman, Huynh, Kevin, Brauner, Barbara, Louie, Gregory, Kueider-Paisley, Alexandra, Suhre, Karsten, Saykin, Andrew J., Ekroos, Kim, Meikle, Peter J., Hood, Leroy, Price, Nathan D., Doraiswamy, P. Murali, Funk, Cory C., Hernández, A. Iván, Kastenmüller, Gabi, Baillie, Rebecca, Han, Xianlin, Kaddurah-Daouk, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547905/
https://www.ncbi.nlm.nih.gov/pubmed/36209301
http://dx.doi.org/10.1038/s42003-022-04011-6

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