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Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation
Racial/ethnic disparities persist in patients' access to living donor kidney transplantation (LDKT). This study assessed the impact of having available potential living donors (PLDs) on candidates' receipt of a kidney transplant (KT) and LDKT at two KT programs. Using data from our clinica...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547969/ https://www.ncbi.nlm.nih.gov/pubmed/35524363 http://dx.doi.org/10.1111/ajt.17090 |
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author | Gordon, Elisa J. Lee, Jungwha Kang, Raymond Caicedo, Juan Carlos |
author_facet | Gordon, Elisa J. Lee, Jungwha Kang, Raymond Caicedo, Juan Carlos |
author_sort | Gordon, Elisa J. |
collection | PubMed |
description | Racial/ethnic disparities persist in patients' access to living donor kidney transplantation (LDKT). This study assessed the impact of having available potential living donors (PLDs) on candidates' receipt of a kidney transplant (KT) and LDKT at two KT programs. Using data from our clinical trial of waitlisted candidates (January 1, 2014–December 31, 2019), we evaluated Hispanic and Non‐Hispanic White (NHW) KT candidates' number of PLDs. Multivariable logistic regression assessed the impact of PLDs on transplantation (KT vs. no KT; for KT recipients, LDKT vs. deceased donor KT). A total of 847 candidates were included, identifying as Hispanic (45.8%) or NHW (54.2%). For Site A, both Hispanic (adjusted OR = 2.26 [95% CI 1.13–4.53]) and NHW (OR = 2.42 [1.10–5.33]) candidates with PLDs completing the questionnaire were more likely to receive a KT. For Site B, candidates with PLDs were not significantly more likely to receive KT. Among KT recipients at both sites, Hispanic (Site A: OR = 21.22 [2.44–184.88]; Site B: OR = 25.54 [7.52–101.54]), and NHW (Site A: OR = 37.70 [6.59–215.67]; Site B: OR = 15.18 [5.64–40.85]) recipients with PLD(s) were significantly more likely to receive a LDKT. Our findings suggest that PLDs increased candidates' likelihood of KT receipt, particularly LDKT. Transplant programs should help candidates identify PLDs early in transplant evaluation. |
format | Online Article Text |
id | pubmed-9547969 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95479692022-12-28 Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation Gordon, Elisa J. Lee, Jungwha Kang, Raymond Caicedo, Juan Carlos Am J Transplant Brief Communications Racial/ethnic disparities persist in patients' access to living donor kidney transplantation (LDKT). This study assessed the impact of having available potential living donors (PLDs) on candidates' receipt of a kidney transplant (KT) and LDKT at two KT programs. Using data from our clinical trial of waitlisted candidates (January 1, 2014–December 31, 2019), we evaluated Hispanic and Non‐Hispanic White (NHW) KT candidates' number of PLDs. Multivariable logistic regression assessed the impact of PLDs on transplantation (KT vs. no KT; for KT recipients, LDKT vs. deceased donor KT). A total of 847 candidates were included, identifying as Hispanic (45.8%) or NHW (54.2%). For Site A, both Hispanic (adjusted OR = 2.26 [95% CI 1.13–4.53]) and NHW (OR = 2.42 [1.10–5.33]) candidates with PLDs completing the questionnaire were more likely to receive a KT. For Site B, candidates with PLDs were not significantly more likely to receive KT. Among KT recipients at both sites, Hispanic (Site A: OR = 21.22 [2.44–184.88]; Site B: OR = 25.54 [7.52–101.54]), and NHW (Site A: OR = 37.70 [6.59–215.67]; Site B: OR = 15.18 [5.64–40.85]) recipients with PLD(s) were significantly more likely to receive a LDKT. Our findings suggest that PLDs increased candidates' likelihood of KT receipt, particularly LDKT. Transplant programs should help candidates identify PLDs early in transplant evaluation. John Wiley and Sons Inc. 2022-05-24 2022-10 /pmc/articles/PMC9547969/ /pubmed/35524363 http://dx.doi.org/10.1111/ajt.17090 Text en © 2022 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Brief Communications Gordon, Elisa J. Lee, Jungwha Kang, Raymond Caicedo, Juan Carlos Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title | Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title_full | Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title_fullStr | Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title_full_unstemmed | Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title_short | Impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
title_sort | impact of having potential living donors on ethnic/racial disparities in access to kidney transplantation |
topic | Brief Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9547969/ https://www.ncbi.nlm.nih.gov/pubmed/35524363 http://dx.doi.org/10.1111/ajt.17090 |
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