The Use of Chromagen Lenses in Different Ocular and Non-ocular Conditions: A Prospective Cohort Study

Background In this study, we aimed to evaluate the efficacy of chromagen lenses and compare the pre- and post-intervention outcomes among individuals with non-ocular conditions such as dyslexia and Irlen syndrome and ocular conditions such as color vision deficiency (CVD) and cone-rod dystrophy (CRD). Methodology This prospective cohort study was conducted from 2016 to 2021 among cases (seven years or older) who were diagnosed with dyslexia, Irlen syndrome, CVD, or CRD. Participants were given a short questionnaire to read, followed by asking direct questions regarding medical health history, ocular history, eyeglasses prescription, and a full orthoptics evaluation. The main outcomes were the improvement in reading speed, reading accuracy, and visual stress. Results A total of 156 patients were included in this study; 110 patients with dyslexia, 19 with Irlen syndrome, 16 with CVD, and 11 with CRD. The findings showed that the reading speed and accuracy were improved in 96.34% of patients with dyslexia and 78.9% of patients with Irlen syndrome. The use of a chromagen lens was significantly associated with visual stress improvement in 89.8% of patients (p = 0.02). Photosensitivity was significantly improved after wearing the chromagen lenses in patients with CVD (87.5%) and CRD (63.6%). Conclusions The study findings showed a positive impact of chromagen lenses on reducing visual stress, including reading speed and accuracy, in patients with dyslexia and Irlen syndrome. Photosensitivity improved in patients with Irlen syndrome and CRD. Color vision was enhanced in patients with CVD. However, further studies are required to investigate the predictors of improvement and assess the long-term efficacy of chromagen lenses on daily activities and learning skills.