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New mechanism for mesenchymal stem cell microvesicle to restore lung permeability: intracellular S1P signaling pathway independent of S1P receptor-1

BACKGROUND: Microvesicles (MVs) derived from human bone marrow mesenchymal stem cell (MSC) were demonstrated to restore lung protein permeability and attenuate acute lung injury. In our previous study, we found that MSC MV increased sphingosine-1-phosphate (S1P) kinase1 mRNA levels in injured human...

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Detalles Bibliográficos
Autores principales:	Ye, Lifang, Song, Jieqiong, Zheng, Yijun, Zhong, Ming, Liu, Jun, Zhu, Duming, Hu, Shuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548125/ https://www.ncbi.nlm.nih.gov/pubmed/36209115 http://dx.doi.org/10.1186/s13287-022-03177-4

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