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Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling

BACKGROUND: MicroRNAs are a type of non-coding single-stranded RNA, which is involved in the regulation of ovary insulin resistance (IR). This study aims to explore the underlying mechanisms of miR-133a-3p regulating ovary IR in obese polycystic ovary syndrome (PCOS). METHODS: Granulosa cells (GCs)...

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Detalles Bibliográficos
Autores principales:	Yang, Xiaoman, Wang, Kehua, Lang, Jiajia, Guo, Danyang, Gao, Haixia, Qiu, Yue, Jin, Xiaohan, Zhang, Mingyue, Shi, Jiaxiu, Ma, QianQian, Ma, Qian, Wen, Zixi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548189/ https://www.ncbi.nlm.nih.gov/pubmed/36209087 http://dx.doi.org/10.1186/s12905-022-01994-6

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