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Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways
Abdominal aortic aneurysm (AAA) represents the serious vascular degenerative disorder, which causes high incidence and mortality. Alpha-ketoglutarate (AKG), a crucial metabolite in the tricarboxylic acid (TCA) cycle, has been reported to exert significant actions on the oxidative stress and inflamma...
Autores principales: | Liu, Junjun, Liu, Mingyuan, Feng, Jiaxuan, Zhu, Hongqiao, Wu, Jianlie, Zhang, Heng, Xiao, Shun, Jing, Zaiping, Zhou, Jian, Niu, Haitao, Guo, Mingjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548204/ https://www.ncbi.nlm.nih.gov/pubmed/36209172 http://dx.doi.org/10.1186/s12967-022-03659-2 |
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