Correlation between molar activity, injection mass and uptake of the PARP targeting radiotracer [(18)F]olaparib in mouse models of glioma

PURPOSE: Radiopharmaceuticals targeting poly(ADP-ribose) polymerase (PARP) have emerged as promising agents for cancer diagnosis and therapy. PARP enzymes are expressed in both cancerous and normal tissue. Hence, the injected mass, molar activity and potential pharmacological effects are important c...

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Detalles Bibliográficos
Autores principales: Chan, Chung Ying, Hopkins, Samantha L., Guibbal, Florian, Pacelli, Anna, Baguña Torres, Julia, Mosley, Michael, Lau, Doreen, Isenegger, Patrick, Chen, Zijun, Wilson, Thomas C., Dias, Gemma, Hueting, Rebekka, Gouverneur, Véronique, Cornelissen, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548459/
https://www.ncbi.nlm.nih.gov/pubmed/36210377
http://dx.doi.org/10.1186/s13550-022-00940-9

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