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Dynamics of transcriptome and chromatin accessibility revealed sequential regulation of potential transcription factors during the brown adipose tissue whitening in rabbits

Brown adipose tissue (BAT) represents a valuable target for treating obesity in humans. BAT losses of thermogenic capacity and gains a “white adipose tissue-like (WAT-like)” phenotype (BAT whitening) under thermoneutral environments, which could lead to potential low therapy responsiveness in BAT-ba...

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Detalles Bibliográficos
Autores principales:	Du, Kun, Chen, Guan-He, Bai, Xue, Chen, Li, Hu, Shen-Qiang, Li, Yan-Hong, Wang, Guo-Ze, He, Jing-Wei, Lai, Song-Jia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548568/ https://www.ncbi.nlm.nih.gov/pubmed/36225319 http://dx.doi.org/10.3389/fcell.2022.981661

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