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Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance

BACKGROUND: The differentiation between myxomas and myxoid liposarcomas (MLPS) often is a serious challenge for the radiologists. Magnetic resonance imaging (MRI) is the most useful imaging technique in characterization of the soft tissue tumors (STT). PURPOSE: To evaluate in a sample of myxomas and...

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Autores principales: Morán, Luz M, Vega, Jesús, Gómez-León, Nieves, Royuela, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549112/
https://www.ncbi.nlm.nih.gov/pubmed/36225896
http://dx.doi.org/10.1177/20584601221131481
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author Morán, Luz M
Vega, Jesús
Gómez-León, Nieves
Royuela, Ana
author_facet Morán, Luz M
Vega, Jesús
Gómez-León, Nieves
Royuela, Ana
author_sort Morán, Luz M
collection PubMed
description BACKGROUND: The differentiation between myxomas and myxoid liposarcomas (MLPS) often is a serious challenge for the radiologists. Magnetic resonance imaging (MRI) is the most useful imaging technique in characterization of the soft tissue tumors (STT). PURPOSE: To evaluate in a sample of myxomas and MLPS of the extremities, what morphological findings in conventional MRI allow us to differentiate these two types of myxoid tumors, in addition to analyzing the validity of the apparent diffusion coefficient (ADC) values of diffusion-weighted MRI (DW-MRI). MATERIAL AND METHODS: Magnetic resonance imaging studies in myxomas and MLPS of extremities searched in our PACS between 2015 and 2019. All studies had conventional MRI with T1, T2, and PD SPAIR sequences, while DW-MRI with ADC mapping and perfusion MRI with a T1 sequence repeated for 4 minutes after contrast injection were additional sequences only in some explorations. Two radiologists evaluated independently the MRI studies by examining the qualitative parameters. Apparent diffusion coefficient values were calculated using two methods—ADC global and ADC solid, and Receiver Operating Characteristic (ROC) curves were applied for analysis. RESULTS: The features were consistent with MLPS: size greater than 10 cm, heterogeneous signal on T1, and nodular enhancement, while the common findings for myxomas were a homogenously hypointense signal on T1 and diffuse peritumoral enhancement. The solid and global ADC values were higher in myxomas. We observed that the solid ADC value less than 2.06 x 10(−3)mm(2) x s would support the diagnosis of MLPS against myxoma. CONCLUSION: Overall, MRI with its different modalities improved the diagnostic accuracy when differentiating myxomas from MLPS of extremities.
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spelling pubmed-95491122022-10-11 Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance Morán, Luz M Vega, Jesús Gómez-León, Nieves Royuela, Ana Acta Radiol Open Original Article BACKGROUND: The differentiation between myxomas and myxoid liposarcomas (MLPS) often is a serious challenge for the radiologists. Magnetic resonance imaging (MRI) is the most useful imaging technique in characterization of the soft tissue tumors (STT). PURPOSE: To evaluate in a sample of myxomas and MLPS of the extremities, what morphological findings in conventional MRI allow us to differentiate these two types of myxoid tumors, in addition to analyzing the validity of the apparent diffusion coefficient (ADC) values of diffusion-weighted MRI (DW-MRI). MATERIAL AND METHODS: Magnetic resonance imaging studies in myxomas and MLPS of extremities searched in our PACS between 2015 and 2019. All studies had conventional MRI with T1, T2, and PD SPAIR sequences, while DW-MRI with ADC mapping and perfusion MRI with a T1 sequence repeated for 4 minutes after contrast injection were additional sequences only in some explorations. Two radiologists evaluated independently the MRI studies by examining the qualitative parameters. Apparent diffusion coefficient values were calculated using two methods—ADC global and ADC solid, and Receiver Operating Characteristic (ROC) curves were applied for analysis. RESULTS: The features were consistent with MLPS: size greater than 10 cm, heterogeneous signal on T1, and nodular enhancement, while the common findings for myxomas were a homogenously hypointense signal on T1 and diffuse peritumoral enhancement. The solid and global ADC values were higher in myxomas. We observed that the solid ADC value less than 2.06 x 10(−3)mm(2) x s would support the diagnosis of MLPS against myxoma. CONCLUSION: Overall, MRI with its different modalities improved the diagnostic accuracy when differentiating myxomas from MLPS of extremities. SAGE Publications 2022-10-07 /pmc/articles/PMC9549112/ /pubmed/36225896 http://dx.doi.org/10.1177/20584601221131481 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Morán, Luz M
Vega, Jesús
Gómez-León, Nieves
Royuela, Ana
Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title_full Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title_fullStr Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title_full_unstemmed Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title_short Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
title_sort myxomas and myxoid liposarcomas of the extremities: our preliminary findings in conventional, perfusion, and diffusion magnetic resonance
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549112/
https://www.ncbi.nlm.nih.gov/pubmed/36225896
http://dx.doi.org/10.1177/20584601221131481
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