Upregulation of TLR4/MyD88 pathway in alcohol-induced Wernicke’s encephalopathy: Findings in preclinical models and in a postmortem human case

Wernicke’s encephalopathy (WE) is a neurologic disease caused by vitamin B1 or thiamine deficiency (TD), being the alcohol use disorder its main risk factor. WE patients present limiting motor, cognitive, and emotional alterations related to a selective cerebral vulnerability. Neuroinflammation has...

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Detalles Bibliográficos
Autores principales: Moya, Marta, Escudero, Berta, Gómez-Blázquez, Elena, Rebolledo-Poves, Ana Belen, López-Gallardo, Meritxell, Guerrero, Carmen, Marco, Eva M., Orio, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549119/
https://www.ncbi.nlm.nih.gov/pubmed/36225571
http://dx.doi.org/10.3389/fphar.2022.866574

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