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Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report

Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be...

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Autores principales: Nishikura, Nozomi, Ohta, Ryuichi, Katagiri, Noritaka, Okayasu, Tatsuhiko, Sano, Chiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549259/
https://www.ncbi.nlm.nih.gov/pubmed/36249629
http://dx.doi.org/10.7759/cureus.28996
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author Nishikura, Nozomi
Ohta, Ryuichi
Katagiri, Noritaka
Okayasu, Tatsuhiko
Sano, Chiaki
author_facet Nishikura, Nozomi
Ohta, Ryuichi
Katagiri, Noritaka
Okayasu, Tatsuhiko
Sano, Chiaki
author_sort Nishikura, Nozomi
collection PubMed
description Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be cured with a small dose of prednisolone without immunosuppressants. Here, we report a case of a 90-year-old patient with the chief complaint of appetite loss and purpura on the legs who was diagnosed with IgA vasculitis based on biopsy results. The patient was initially treated with prednisolone effectively but exacerbated with steroid tapering, eventually requiring the use of an immunosuppressant. This case highlights the importance of monitoring the symptoms of IgA vasculitis while tapering steroids and clarifying the timing of immunosuppressant initiation.
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spelling pubmed-95492592022-10-14 Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report Nishikura, Nozomi Ohta, Ryuichi Katagiri, Noritaka Okayasu, Tatsuhiko Sano, Chiaki Cureus Family/General Practice Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be cured with a small dose of prednisolone without immunosuppressants. Here, we report a case of a 90-year-old patient with the chief complaint of appetite loss and purpura on the legs who was diagnosed with IgA vasculitis based on biopsy results. The patient was initially treated with prednisolone effectively but exacerbated with steroid tapering, eventually requiring the use of an immunosuppressant. This case highlights the importance of monitoring the symptoms of IgA vasculitis while tapering steroids and clarifying the timing of immunosuppressant initiation. Cureus 2022-09-10 /pmc/articles/PMC9549259/ /pubmed/36249629 http://dx.doi.org/10.7759/cureus.28996 Text en Copyright © 2022, Nishikura et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Nishikura, Nozomi
Ohta, Ryuichi
Katagiri, Noritaka
Okayasu, Tatsuhiko
Sano, Chiaki
Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title_full Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title_fullStr Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title_full_unstemmed Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title_short Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
title_sort refractory immunoglobulin a (iga) vasculitis in an elderly patient: a case report
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549259/
https://www.ncbi.nlm.nih.gov/pubmed/36249629
http://dx.doi.org/10.7759/cureus.28996
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