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Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report
Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549259/ https://www.ncbi.nlm.nih.gov/pubmed/36249629 http://dx.doi.org/10.7759/cureus.28996 |
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author | Nishikura, Nozomi Ohta, Ryuichi Katagiri, Noritaka Okayasu, Tatsuhiko Sano, Chiaki |
author_facet | Nishikura, Nozomi Ohta, Ryuichi Katagiri, Noritaka Okayasu, Tatsuhiko Sano, Chiaki |
author_sort | Nishikura, Nozomi |
collection | PubMed |
description | Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be cured with a small dose of prednisolone without immunosuppressants. Here, we report a case of a 90-year-old patient with the chief complaint of appetite loss and purpura on the legs who was diagnosed with IgA vasculitis based on biopsy results. The patient was initially treated with prednisolone effectively but exacerbated with steroid tapering, eventually requiring the use of an immunosuppressant. This case highlights the importance of monitoring the symptoms of IgA vasculitis while tapering steroids and clarifying the timing of immunosuppressant initiation. |
format | Online Article Text |
id | pubmed-9549259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-95492592022-10-14 Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report Nishikura, Nozomi Ohta, Ryuichi Katagiri, Noritaka Okayasu, Tatsuhiko Sano, Chiaki Cureus Family/General Practice Immunoglobulin A (IgA) vasculitis is small-vessel arteritis triggered by autoimmunity and allergies. IgA vasculitis among elderly patients is rare, and there is a lack of evidence regarding the choice of medicine and treatment duration. The main treatment for IgA vasculitis is steroids which can be cured with a small dose of prednisolone without immunosuppressants. Here, we report a case of a 90-year-old patient with the chief complaint of appetite loss and purpura on the legs who was diagnosed with IgA vasculitis based on biopsy results. The patient was initially treated with prednisolone effectively but exacerbated with steroid tapering, eventually requiring the use of an immunosuppressant. This case highlights the importance of monitoring the symptoms of IgA vasculitis while tapering steroids and clarifying the timing of immunosuppressant initiation. Cureus 2022-09-10 /pmc/articles/PMC9549259/ /pubmed/36249629 http://dx.doi.org/10.7759/cureus.28996 Text en Copyright © 2022, Nishikura et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Family/General Practice Nishikura, Nozomi Ohta, Ryuichi Katagiri, Noritaka Okayasu, Tatsuhiko Sano, Chiaki Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title | Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title_full | Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title_fullStr | Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title_full_unstemmed | Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title_short | Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report |
title_sort | refractory immunoglobulin a (iga) vasculitis in an elderly patient: a case report |
topic | Family/General Practice |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549259/ https://www.ncbi.nlm.nih.gov/pubmed/36249629 http://dx.doi.org/10.7759/cureus.28996 |
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