Cargando…
Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field
Plants and animals serve as hosts for microbes. To protect themselves from microbe-induced damage, plants and animals need to differentiate self-molecules/signals from non-self, microbe-derived molecules. Damage-associated molecular patterns (DAMPs) are danger signals released from the damaged host...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549290/ https://www.ncbi.nlm.nih.gov/pubmed/36226289 http://dx.doi.org/10.3389/fpls.2022.864086 |
_version_ | 1784805638102056960 |
---|---|
author | Kim, Doyeon Riu, Myoungjoo Oh, Sang-Keun Ryu, Choong-Min |
author_facet | Kim, Doyeon Riu, Myoungjoo Oh, Sang-Keun Ryu, Choong-Min |
author_sort | Kim, Doyeon |
collection | PubMed |
description | Plants and animals serve as hosts for microbes. To protect themselves from microbe-induced damage, plants and animals need to differentiate self-molecules/signals from non-self, microbe-derived molecules. Damage-associated molecular patterns (DAMPs) are danger signals released from the damaged host tissue or present on the surface of stressed cells. Although a self-extracellular DNA has previously been shown to act as a DAMP in different plant species, the existence of a self-extracellular RNA (eRNA) as a danger signal in plants remains unknown. Here, we firstly evaluated the ability of a pepper self-eRNA to activate immunity against viral and bacterial pathogens under field conditions. Pepper leaves pre-infiltrated with self-eRNA exhibited reduced titer of the naturally occurring Tomato spotted wilt virus and diminished symptoms of Xanthomonas axonopodis pv. vesicatoria infection through eliciting defense priming of abscisic acid signaling. At the end of the growing season at 90 days after transplanting, pepper plants treated with self- and non-self-eRNAs showed no difference in fruit yield. Taken together, our discovery demonstrated that self-eRNA can successfully activate plant systemic immunity without any growth penalty, indicating its potential as a novel disease management agent against a broad range of pathogenic microbes. |
format | Online Article Text |
id | pubmed-9549290 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95492902022-10-11 Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field Kim, Doyeon Riu, Myoungjoo Oh, Sang-Keun Ryu, Choong-Min Front Plant Sci Plant Science Plants and animals serve as hosts for microbes. To protect themselves from microbe-induced damage, plants and animals need to differentiate self-molecules/signals from non-self, microbe-derived molecules. Damage-associated molecular patterns (DAMPs) are danger signals released from the damaged host tissue or present on the surface of stressed cells. Although a self-extracellular DNA has previously been shown to act as a DAMP in different plant species, the existence of a self-extracellular RNA (eRNA) as a danger signal in plants remains unknown. Here, we firstly evaluated the ability of a pepper self-eRNA to activate immunity against viral and bacterial pathogens under field conditions. Pepper leaves pre-infiltrated with self-eRNA exhibited reduced titer of the naturally occurring Tomato spotted wilt virus and diminished symptoms of Xanthomonas axonopodis pv. vesicatoria infection through eliciting defense priming of abscisic acid signaling. At the end of the growing season at 90 days after transplanting, pepper plants treated with self- and non-self-eRNAs showed no difference in fruit yield. Taken together, our discovery demonstrated that self-eRNA can successfully activate plant systemic immunity without any growth penalty, indicating its potential as a novel disease management agent against a broad range of pathogenic microbes. Frontiers Media S.A. 2022-09-26 /pmc/articles/PMC9549290/ /pubmed/36226289 http://dx.doi.org/10.3389/fpls.2022.864086 Text en Copyright © 2022 Kim, Riu, Oh and Ryu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Plant Science Kim, Doyeon Riu, Myoungjoo Oh, Sang-Keun Ryu, Choong-Min Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title | Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title_full | Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title_fullStr | Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title_full_unstemmed | Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title_short | Extracellular self-RNA: A danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
title_sort | extracellular self-rna: a danger elicitor in pepper induces immunity against bacterial and viral pathogens in the field |
topic | Plant Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549290/ https://www.ncbi.nlm.nih.gov/pubmed/36226289 http://dx.doi.org/10.3389/fpls.2022.864086 |
work_keys_str_mv | AT kimdoyeon extracellularselfrnaadangerelicitorinpepperinducesimmunityagainstbacterialandviralpathogensinthefield AT riumyoungjoo extracellularselfrnaadangerelicitorinpepperinducesimmunityagainstbacterialandviralpathogensinthefield AT ohsangkeun extracellularselfrnaadangerelicitorinpepperinducesimmunityagainstbacterialandviralpathogensinthefield AT ryuchoongmin extracellularselfrnaadangerelicitorinpepperinducesimmunityagainstbacterialandviralpathogensinthefield |