A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease

Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So in this...

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Autores principales: Ahmad, Faizan, Sachdeva, Punya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
THEMED SECTION: COGNITIVE IMPAIRMENT IN THE ELDERLY
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549310/
https://www.ncbi.nlm.nih.gov/pubmed/36247342
http://dx.doi.org/10.1002/agm2.12216
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author Ahmad, Faizan
Sachdeva, Punya
author_facet Ahmad, Faizan
Sachdeva, Punya
author_sort Ahmad, Faizan
collection PubMed
description Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So in this review, we are focusing on stem cell therapy for AD. This review will cover all stem cells like mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, and neural stem cells. Clinical trials of AD have also been discussed. Finally, limitations of stem cells are discussed with ongoing clinical trials, and in the future stem cell therapy can be used for treatment of AD.
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spelling pubmed-95493102022-10-14 A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease Ahmad, Faizan Sachdeva, Punya Aging Med (Milton) THEMED SECTION: COGNITIVE IMPAIRMENT IN THE ELDERLY Alzheimer's disease (AD) is one of the most common forms of dementia and affects around 50 million people around the globe. AD is diagnosed mainly through imaging techniques and to date only five drugs are approved for management of AD but no promising treatment is available for AD. So in this review, we are focusing on stem cell therapy for AD. This review will cover all stem cells like mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells, and neural stem cells. Clinical trials of AD have also been discussed. Finally, limitations of stem cells are discussed with ongoing clinical trials, and in the future stem cell therapy can be used for treatment of AD. John Wiley and Sons Inc. 2022-07-25 /pmc/articles/PMC9549310/ /pubmed/36247342 http://dx.doi.org/10.1002/agm2.12216 Text en © 2022 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle THEMED SECTION: COGNITIVE IMPAIRMENT IN THE ELDERLY
Ahmad, Faizan
Sachdeva, Punya
A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title_full A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title_fullStr A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title_full_unstemmed A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title_short A consolidated review on stem cell therapy for treatment and management of Alzheimer's disease
title_sort consolidated review on stem cell therapy for treatment and management of alzheimer's disease
topic THEMED SECTION: COGNITIVE IMPAIRMENT IN THE ELDERLY
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549310/
https://www.ncbi.nlm.nih.gov/pubmed/36247342
http://dx.doi.org/10.1002/agm2.12216
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