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Selective miRNA inhibition in CD8(+) cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses

miRNAs dictate relevant virus-host interactions, offering new avenues for interventions to achieve an HIV remission. We aimed to enhance HIV-specific cytotoxic responses—a hallmark of natural HIV control— by miRNA modulation in T cells. We recruited 12 participants six elite controllers and six pati...

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Detalles Bibliográficos
Autores principales: Madrid-Elena, Nadia, Serrano-Villar, Sergio, Gutiérrez, Carolina, Sastre, Beatriz, Morín, Matías, Luna, Laura, Martín, Laura, Santoyo-López, Javier, López-Huertas, María Rosa, Moreno, Elena, García-Bermejo, María Laura, Moreno-Pelayo, Miguel Ángel, Moreno, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549323/
https://www.ncbi.nlm.nih.gov/pubmed/36225912
http://dx.doi.org/10.3389/fimmu.2022.998368