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Insights into an NEk2 inhibitory profile of nitidine chloride by molecular docking and biological evaluation

Deregulation of NEK2(NIMA-related serine/threonine 2) confers chemotherapeutic resistance to apoptosis and is closely correlated with poor prognosis in hepatocellular carcinoma (HCC). Here, we find that nanoparticles are prepared through hemisynthesis from natural nitidine chloride (NC) with enhance...

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Detalles Bibliográficos
Autores principales:	Li, Danni, Lu, Jiahao, Zhang, Qiying, Zhou, Yuzhu, Li, Long, Zhu, Hua, Li, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549606/ https://www.ncbi.nlm.nih.gov/pubmed/36210464 http://dx.doi.org/10.1186/s13065-022-00870-6

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