Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model

BACKGROUND: Despite widespread searches, there are currently no validated biofluid markers for the detection of subclinical neuroinflammation in multiple sclerosis (MS). The dynamic nature of human metabolism in response to changes in homeostasis, as measured by metabolomics, may allow early identif...

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Detalles Bibliográficos
Autores principales: Yeo, Tianrong, Bayuangga, Halwan, Augusto-Oliveira, Marcus, Sealey, Megan, Claridge, Timothy D. W., Tanner, Rachel, Leppert, David, Palace, Jacqueline, Kuhle, Jens, Probert, Fay, Anthony, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549622/
https://www.ncbi.nlm.nih.gov/pubmed/36210459
http://dx.doi.org/10.1186/s12974-022-02614-8

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