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Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer’s disease in TgF344-AD rats

BACKGROUND: Imbalanced synaptic transmission appears to be an early driver in Alzheimer’s disease (AD) leading to brain network alterations. Early detection of altered synaptic transmission and insight into mechanisms causing early synaptic alterations would be valuable treatment strategies. This st...

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Detalles Bibliográficos
Autores principales: van den Berg, Monica, Adhikari, Mohit H., Verschuuren, Marlies, Pintelon, Isabel, Vasilkovska, Tamara, Van Audekerke, Johan, Missault, Stephan, Heymans, Loran, Ponsaerts, Peter, De Vos, Winnok H., Van der Linden, Annemie, Keliris, Georgios A., Verhoye, Marleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549630/
https://www.ncbi.nlm.nih.gov/pubmed/36217211
http://dx.doi.org/10.1186/s13195-022-01089-2