Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis

BACKGROUND: Papillary thyroid carcinoma (PTC) is one of the most common forms of thyroid cancer with a cure rate of over 90% after surgery. However, aggressive forms may still occur, and personalized therapeutic strategies are increasingly required. METHODS: We performed integrated genomic and prote...

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Detalles Bibliográficos
Autores principales: Renaud, Emilie, Riegel, Kristina, Romero, Rossana, Suryamohan, Kushal, Distler, Ute, Tenzer, Stefan, Schad, Arno, Musholt, Thomas J., Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549631/
https://www.ncbi.nlm.nih.gov/pubmed/36217175
http://dx.doi.org/10.1186/s12943-022-01665-y

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