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Promoted CD4(+) T cell-derived IFN-γ/IL-10 by photobiomodulation therapy modulates neurogenesis to ameliorate cognitive deficits in APP/PS1 and 3xTg-AD mice

BACKGROUND: The immune system has been implicated in synaptic plasticity, inflammation, and the progression of Alzheimer's disease (AD). However, there were few studies on improving the niche microenvironment of neural stem cells (NSCs) in the brain of AD to promote adult hippocampal neurogenes...

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Detalles Bibliográficos
Autores principales: Wu, Xiaolei, Shen, Qi, Chang, Haocai, Li, Junyu, Xing, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549637/
https://www.ncbi.nlm.nih.gov/pubmed/36217178
http://dx.doi.org/10.1186/s12974-022-02617-5