Contaminating transfection complexes can masquerade as small extracellular vesicles and impair their delivery of RNA

One of the functions of small extracellular vesicles (sEVs) which has received the most attention is their capacity to deliver RNA into the cytoplasm of target cells. These studies have often been performed by transfecting RNAs into sEV‐producing cells, to later purify and study sEV delivery of RNA....

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Detalles Bibliográficos
Autores principales: McCann, Jenna, Sosa‐Miranda, Carmen Daniela, Guo, Huishan, Reshke, Ryan, Savard, Alexandre, Zardini Buzatto, Adriana, Taylor, James A., Li, Liang, Gibbings, Derrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Technical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549735/
https://www.ncbi.nlm.nih.gov/pubmed/36214496
http://dx.doi.org/10.1002/jev2.12220

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