The impact of RNA modifications on the biology of DNA virus infection

Approximately 170 RNA modifications have been identified and these are critical for determining the fate and function of cellular RNAs. Similar to human transcripts, viral RNAs possess an extensive RNA modification landscape. While initial efforts largely focused on investigating the RNA modificatio...

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Autores principales: Rajendren, Suba, Karijolich, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549750/
https://www.ncbi.nlm.nih.gov/pubmed/35623231
http://dx.doi.org/10.1016/j.ejcb.2022.151239
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author Rajendren, Suba
Karijolich, John
author_facet Rajendren, Suba
Karijolich, John
author_sort Rajendren, Suba
collection PubMed
description Approximately 170 RNA modifications have been identified and these are critical for determining the fate and function of cellular RNAs. Similar to human transcripts, viral RNAs possess an extensive RNA modification landscape. While initial efforts largely focused on investigating the RNA modification landscape in the context of RNA virus infection, a growing body of work has explored the impact of RNA modifications on DNA virus biology. These studies have revealed roles for RNA modifications in DNA virus infection, including gene regulation and viral pathogenesis. In this review, we will discuss the current knowledge on how RNA modifications impact DNA virus biology.
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spelling pubmed-95497502022-10-10 The impact of RNA modifications on the biology of DNA virus infection Rajendren, Suba Karijolich, John Eur J Cell Biol Article Approximately 170 RNA modifications have been identified and these are critical for determining the fate and function of cellular RNAs. Similar to human transcripts, viral RNAs possess an extensive RNA modification landscape. While initial efforts largely focused on investigating the RNA modification landscape in the context of RNA virus infection, a growing body of work has explored the impact of RNA modifications on DNA virus biology. These studies have revealed roles for RNA modifications in DNA virus infection, including gene regulation and viral pathogenesis. In this review, we will discuss the current knowledge on how RNA modifications impact DNA virus biology. 2022 2022-05-21 /pmc/articles/PMC9549750/ /pubmed/35623231 http://dx.doi.org/10.1016/j.ejcb.2022.151239 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Article
Rajendren, Suba
Karijolich, John
The impact of RNA modifications on the biology of DNA virus infection
title The impact of RNA modifications on the biology of DNA virus infection
title_full The impact of RNA modifications on the biology of DNA virus infection
title_fullStr The impact of RNA modifications on the biology of DNA virus infection
title_full_unstemmed The impact of RNA modifications on the biology of DNA virus infection
title_short The impact of RNA modifications on the biology of DNA virus infection
title_sort impact of rna modifications on the biology of dna virus infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549750/
https://www.ncbi.nlm.nih.gov/pubmed/35623231
http://dx.doi.org/10.1016/j.ejcb.2022.151239
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