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A telemonitoring programme in patients with heart failure in France: a cost-utility analysis

BACKGROUND: Certain telemedicine programmes for heart failure (HF) have been shown to reduce all-cause mortality and heart failure-related hospitalisations, but their cost-effectiveness remains controversial. The SCAD programme is a home-based interactive telemonitoring service for HF, which is one...

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Autores principales: Caillon, Mégane, Sabatier, Rémi, Legallois, Damien, Courouve, Laurène, Donio, Valérie, Boudevin, Florence, de Chalus, Thibault, Hauchard, Karine, Belin, Annette, Milliez, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549824/
https://www.ncbi.nlm.nih.gov/pubmed/36217130
http://dx.doi.org/10.1186/s12872-022-02878-1
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author Caillon, Mégane
Sabatier, Rémi
Legallois, Damien
Courouve, Laurène
Donio, Valérie
Boudevin, Florence
de Chalus, Thibault
Hauchard, Karine
Belin, Annette
Milliez, Paul
author_facet Caillon, Mégane
Sabatier, Rémi
Legallois, Damien
Courouve, Laurène
Donio, Valérie
Boudevin, Florence
de Chalus, Thibault
Hauchard, Karine
Belin, Annette
Milliez, Paul
author_sort Caillon, Mégane
collection PubMed
description BACKGROUND: Certain telemedicine programmes for heart failure (HF) have been shown to reduce all-cause mortality and heart failure-related hospitalisations, but their cost-effectiveness remains controversial. The SCAD programme is a home-based interactive telemonitoring service for HF, which is one of the largest and longest-running telemonitoring programmes for HF in France. The objective of this cost-utility analysis was to evaluate the cost-effectiveness of the SCAD programme with respect to standard hospital-based care in patients with HF. METHODS: A Markov model simulating hospitalisations and mortality in patients with HF was constructed to estimate outcomes and costs. The model included six distinct health states (three ‘not hospitalised’ states, two ‘hospitalisation for heart failure’ states, both depending on the number of previous hospitalisations, and one death state). The model lifetime in the base case was 10 years. Model inputs were based on published literature. Outputs (costs and QALYs) were compared between SCAD participants and standard care. Deterministic and probabilistic sensitivity analyses were performed to assess uncertainty in the input parameters of the model. RESULTS: The number of quality-adjusted life years (QALYs) was 3.75 in the standard care setting and 4.41 in the SCAD setting. This corresponds to a gain in QALYs provided by the SCAD programme of 0.65 over the 10 years lifetime of the model. The estimated total cost was €30,932 in the standard care setting and €35,177 in the SCAD setting, with an incremental cost of €4245. The incremental cost-effectiveness ratio (ICER) for the SCAD programme over standard care was estimated at €4579/QALY. In the deterministic sensitivity analysis, the variables that had the most impact on the ICER were HF management costs. The likelihood of the SCAD programme being considered cost-effective was 90% at a willingness-to-pay threshold of €11,800. CONCLUSIONS: Enrolment of patients into the SCAD programme is highly cost-effective. Extension of the programme to other hospitals and more patients would have a limited budget impact but provide important clinical benefits. This finding should also be taken into account in new public health policies aimed at encouraging a shift from inpatient to ambulatory care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02878-1.
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spelling pubmed-95498242022-10-11 A telemonitoring programme in patients with heart failure in France: a cost-utility analysis Caillon, Mégane Sabatier, Rémi Legallois, Damien Courouve, Laurène Donio, Valérie Boudevin, Florence de Chalus, Thibault Hauchard, Karine Belin, Annette Milliez, Paul BMC Cardiovasc Disord Research BACKGROUND: Certain telemedicine programmes for heart failure (HF) have been shown to reduce all-cause mortality and heart failure-related hospitalisations, but their cost-effectiveness remains controversial. The SCAD programme is a home-based interactive telemonitoring service for HF, which is one of the largest and longest-running telemonitoring programmes for HF in France. The objective of this cost-utility analysis was to evaluate the cost-effectiveness of the SCAD programme with respect to standard hospital-based care in patients with HF. METHODS: A Markov model simulating hospitalisations and mortality in patients with HF was constructed to estimate outcomes and costs. The model included six distinct health states (three ‘not hospitalised’ states, two ‘hospitalisation for heart failure’ states, both depending on the number of previous hospitalisations, and one death state). The model lifetime in the base case was 10 years. Model inputs were based on published literature. Outputs (costs and QALYs) were compared between SCAD participants and standard care. Deterministic and probabilistic sensitivity analyses were performed to assess uncertainty in the input parameters of the model. RESULTS: The number of quality-adjusted life years (QALYs) was 3.75 in the standard care setting and 4.41 in the SCAD setting. This corresponds to a gain in QALYs provided by the SCAD programme of 0.65 over the 10 years lifetime of the model. The estimated total cost was €30,932 in the standard care setting and €35,177 in the SCAD setting, with an incremental cost of €4245. The incremental cost-effectiveness ratio (ICER) for the SCAD programme over standard care was estimated at €4579/QALY. In the deterministic sensitivity analysis, the variables that had the most impact on the ICER were HF management costs. The likelihood of the SCAD programme being considered cost-effective was 90% at a willingness-to-pay threshold of €11,800. CONCLUSIONS: Enrolment of patients into the SCAD programme is highly cost-effective. Extension of the programme to other hospitals and more patients would have a limited budget impact but provide important clinical benefits. This finding should also be taken into account in new public health policies aimed at encouraging a shift from inpatient to ambulatory care. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02878-1. BioMed Central 2022-10-10 /pmc/articles/PMC9549824/ /pubmed/36217130 http://dx.doi.org/10.1186/s12872-022-02878-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Caillon, Mégane
Sabatier, Rémi
Legallois, Damien
Courouve, Laurène
Donio, Valérie
Boudevin, Florence
de Chalus, Thibault
Hauchard, Karine
Belin, Annette
Milliez, Paul
A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title_full A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title_fullStr A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title_full_unstemmed A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title_short A telemonitoring programme in patients with heart failure in France: a cost-utility analysis
title_sort telemonitoring programme in patients with heart failure in france: a cost-utility analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549824/
https://www.ncbi.nlm.nih.gov/pubmed/36217130
http://dx.doi.org/10.1186/s12872-022-02878-1
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