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Recent findings on the role of wild-type and mutant p53 in cancer development and therapy

The p53 protein is a tumor suppressor encoded by the TP53 gene and consists of 393 amino acids with four main functional domains. This protein responds to various cellular stresses to regulate the expression of target genes, thereby causing DNA repair, cell cycle arrest, apoptosis, metabolic changes...

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Detalles Bibliográficos
Autores principales:	Babamohamadi, Mehregan, Babaei, Esmaeil, Ahmed Salih, Burhan, Babamohammadi, Mahshid, Jalal Azeez, Hewa, Othman, Goran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549909/ https://www.ncbi.nlm.nih.gov/pubmed/36225257 http://dx.doi.org/10.3389/fmolb.2022.903075

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