In vitro and in silico assessment of new beta amino ketones with antiplasmodial activity

BACKGROUND: Based on the current need for new drugs against malaria, our study evaluated eight beta amino ketones in silico and in vitro for potential antimalarial activity. METHODS: Using the Brazilian Malaria Molecular Targets (BraMMT) and OCTOPUS® software programs, the pattern of interactions of...

Descripción completa

Detalles Bibliográficos
Autores principales: Krombauer, Gabriela Camila, Guedes, Karla de Sena, Banfi, Felipe Fingir, Nunes, Renata Rachide, da Fonseca, Amanda Luisa, de Siqueira, Ezequias Pessoa, Bellei, Jéssica Côrrea Bezerra, Scopel, Kézia Katiani Gorza, Varotti, Fernando de Pilla, Sanchez, Bruno Antônio Marinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549944/
https://www.ncbi.nlm.nih.gov/pubmed/36169491
http://dx.doi.org/10.1590/0037-8682-0590-2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549944/
https://www.ncbi.nlm.nih.gov/pubmed/36169491
http://dx.doi.org/10.1590/0037-8682-0590-2022

Ejemplares similares