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NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy

Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a novel target, NOX1, an isoform of superoxide-...

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Detalles Bibliográficos
Autores principales: Zhang, Dandan, Li, Yilan, Wang, Weijie, Lang, Xueyan, Zhang, Yanxiu, Zhao, Qianqian, Yan, Jingru, Zhang, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549956/
https://www.ncbi.nlm.nih.gov/pubmed/36225554
http://dx.doi.org/10.3389/fphar.2022.928762