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NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy
Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a novel target, NOX1, an isoform of superoxide-...
Autores principales: | Zhang, Dandan, Li, Yilan, Wang, Weijie, Lang, Xueyan, Zhang, Yanxiu, Zhao, Qianqian, Yan, Jingru, Zhang, Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549956/ https://www.ncbi.nlm.nih.gov/pubmed/36225554 http://dx.doi.org/10.3389/fphar.2022.928762 |
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