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Right occipital transtentorial approach for a pineal malignant germ cell tumor

Germ cell tumors account for up to 53% of the malignant lesions found in the pineal region and are typically managed with a combination of radiation therapy and chemotherapy. Malignant somatic transformation of intracranial germ cell tumors is exceedingly rare and has only been reported on two other...

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Autores principales: Gill, Brian J. A., Higgins, Dominique M., Banu, Matei A., Argenziano, Michael G., Feldstein, Neil A., Bruce, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549986/
https://www.ncbi.nlm.nih.gov/pubmed/36284916
http://dx.doi.org/10.3171/2021.4.FOCVID2151
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author Gill, Brian J. A.
Higgins, Dominique M.
Banu, Matei A.
Argenziano, Michael G.
Feldstein, Neil A.
Bruce, Jeffrey N.
author_facet Gill, Brian J. A.
Higgins, Dominique M.
Banu, Matei A.
Argenziano, Michael G.
Feldstein, Neil A.
Bruce, Jeffrey N.
author_sort Gill, Brian J. A.
collection PubMed
description Germ cell tumors account for up to 53% of the malignant lesions found in the pineal region and are typically managed with a combination of radiation therapy and chemotherapy. Malignant somatic transformation of intracranial germ cell tumors is exceedingly rare and has only been reported on two other occasions. Here the authors present the case of a pineal yolk sac tumor that failed optimum first-line treatment and underwent malignant somatic transformation to an enteric mucinous adenocarcinoma requiring surgical intervention. This video demonstrates the technical nuances of the occipital transtentorial approach and the safe microsurgical dissection of lesions within the pineal region. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2151.
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spelling pubmed-95499862022-10-24 Right occipital transtentorial approach for a pineal malignant germ cell tumor Gill, Brian J. A. Higgins, Dominique M. Banu, Matei A. Argenziano, Michael G. Feldstein, Neil A. Bruce, Jeffrey N. Neurosurg Focus Video Article Germ cell tumors account for up to 53% of the malignant lesions found in the pineal region and are typically managed with a combination of radiation therapy and chemotherapy. Malignant somatic transformation of intracranial germ cell tumors is exceedingly rare and has only been reported on two other occasions. Here the authors present the case of a pineal yolk sac tumor that failed optimum first-line treatment and underwent malignant somatic transformation to an enteric mucinous adenocarcinoma requiring surgical intervention. This video demonstrates the technical nuances of the occipital transtentorial approach and the safe microsurgical dissection of lesions within the pineal region. The video can be found here: https://stream.cadmore.media/r10.3171/2021.4.FOCVID2151. American Association of Neurological Surgeons 2021-07-01 /pmc/articles/PMC9549986/ /pubmed/36284916 http://dx.doi.org/10.3171/2021.4.FOCVID2151 Text en © 2021, The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the CC BY license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Gill, Brian J. A.
Higgins, Dominique M.
Banu, Matei A.
Argenziano, Michael G.
Feldstein, Neil A.
Bruce, Jeffrey N.
Right occipital transtentorial approach for a pineal malignant germ cell tumor
title Right occipital transtentorial approach for a pineal malignant germ cell tumor
title_full Right occipital transtentorial approach for a pineal malignant germ cell tumor
title_fullStr Right occipital transtentorial approach for a pineal malignant germ cell tumor
title_full_unstemmed Right occipital transtentorial approach for a pineal malignant germ cell tumor
title_short Right occipital transtentorial approach for a pineal malignant germ cell tumor
title_sort right occipital transtentorial approach for a pineal malignant germ cell tumor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549986/
https://www.ncbi.nlm.nih.gov/pubmed/36284916
http://dx.doi.org/10.3171/2021.4.FOCVID2151
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