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POP1 inhibits MSU-induced inflammasome activation and ameliorates gout

Canonical inflammasomes are innate immune protein scaffolds that enable the activation of inflammatory caspase-1, and subsequently the processing and release of interleukin (IL)-1β, IL-18, and danger signals, as well as the induction of pyroptotic cell death. Inflammasome assembly and activation occ...

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Detalles Bibliográficos
Autores principales:	de Almeida, Lucia, Devi, Savita, Indramohan, Mohanalaxmi, Huang, Qi-Quan, Ratsimandresy, Rojo A., Pope, Richard M., Dorfleutner, Andrea, Stehlik, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550078/ https://www.ncbi.nlm.nih.gov/pubmed/36225929 http://dx.doi.org/10.3389/fimmu.2022.912069

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