Randomized, placebo controlled phase I trial of the safety, pharmacokinetics, pharmacodynamics and acceptability of a 90 day tenofovir plus levonorgestrel vaginal ring used continuously or cyclically in women: The CONRAD 138 study

Multipurpose prevention technologies (MPTs), which prevent sexually transmitted infection(s) and unintended pregnancy, are highly desirable to women. In this randomized, placebo-controlled, phase I study, women used a placebo or tenofovir (TFV) and levonorgestrel (LNG) intravaginal ring (IVR), eithe...

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Detalles Bibliográficos
Autores principales: Thurman, Andrea R., Brache, Vivian, Cochon, Leila, Ouattara, Louise A., Chandra, Neelima, Jacot, Terry, Yousefieh, Nazita, Clark, Meredith R., Peet, Melissa, Hanif, Homaira, Schwartz, Jill L., Ju, Susan, Marzinke, Mark A., Erikson, David W., Parikh, Urvi, Herold, Betsy C., Fichorova, Raina N., Tolley, Elizabeth, Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550080/
https://www.ncbi.nlm.nih.gov/pubmed/36215267
http://dx.doi.org/10.1371/journal.pone.0275794

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